Intelligent Drug Delivery Appliance

ABSTRACT

A system, method and apparatus for real time measurement and monitoring of various personal health parameters including controlled delivery of drugs/medications by intelligent pump appliances, intelligent inhalation appliances and intelligent skin patch appliances used in a standalone manner or in a wired or wireless networked configuration, in conjunction with various peripheral devices, other intelligent appliances, servers, RF ID Tags and stationary/mobile devices. The intelligent appliances relate to the measurement, monitoring and delivery of insulin/other drugs for the treatment of diabetes and other diseases. The method also additionally includes the application of intelligent appliances for pain management including visualization of organs and body locations exhibiting pain.

CROSS REFERENCE TO RELATED APPLICATIONS

This application is a continuation of U.S. patent application Ser. No.11/708,269 filed Feb. 20, 2007, which is a continuation of U.S. patentapplication Ser. No. 11/018,862 filed Dec. 19, 2004, and acontinuation-in-part application of U.S. patent application Ser. No.11/001,668 filed Nov. 30, 2004, each of which is incorporated herein byreference in its entirety.

ABBREVIATIONS

Cellular Telephone is abbreviated as CT

Mobile Device is abbreviated as MD

Intelligent Personal Health Management Appliance is abbreviated as IPHMA

Personal Health Management is abbreviated as PHM

Intelligent Skin Patch System is abbreviated as ISPS

Intelligent Activated Skin Patch System is abbreviated as IASPS

The terms Appliance and Device are used interchangeably.

The usage of the word drug refers to medications approved by regulatorybodies for consumption by individuals.

BACKGROUND OF THE INVENTION

There is a need for a new class of intelligent appliances, referred inhere as intelligent personal health management appliances, that enablethe individual to personally acquire one or more types of biologicalinformation in real time, archive said information for correlation withfactors such as diet and other activities including physicalexercise/mental activity/stress and other factors, for personal healthmanagement by the individual him/her self or for personal healthmanagement in conjunction with a qualified health professional. Thepresent invention teaches novel methods and novel appliances for realtime data acquisition of biological information, for archiving said datafor contemporaneous utility or for utility at a selected time, foranalyzing said data, for determining trends, for communication of saiddata/trends to one or more health professionals and for comprehensivereal time management of the personal health of an individual in a costeffective manner in accordance with the quality/cost objectivesacceptable to the individual.

Specifically, the present invention relates to intelligent appliancesfor monitoring the blood sugar level of an individual for management ofdiabetes and related health factors. The incidence of both adultdiabetes and pediatric/juvenile diabetes is increasingly rapidly in mostpopulations as a result of improper diet and lack of exercise. The bloodglucose level is a proven indicator for measuring the level of diabetes.The level of blood glucose in the blood stream is well co-relatable withthe ingestion of various foods, the time from the ingestion of variousfoods, the frequency and amount of ingestion of different foods; andalso the level of physical activity.

While genetics plays a role in determining whether an individual has ahigh probability for being afflicted with diabetes, the onset ofdiabetes and the severity of diabetes are controllable by followingcertain norms of controllable behavior. Neglecting to diagnose, treatand control diabetes may lead to nerve disease, kidney disease, retinaleye disease and in some cases loss of limbs such as toes.

The healthy human body actively controls the level of blood glucoselevels by regulating the amount of insulin production, wherein theinsulin is generated by the pancreas. The treatment of diabetes requiresthat the level of insulin within the body is monitored and managedactively by helping the pancreas generate proper levels of insulininternal to the human body or providing controlled amounts of insulindelivered in a programmed manner from external sources, in conjunctionwith the ingestion of food/dietary habits that is best suited to aspecific individual.

Therefore, there is a need for blood glucose monitoring appliances andalso for insulin delivery appliances to regulate the blood glucose levelwithin the human body. The prior art equipment/devices for monitoringblood glucose levels and or delivery of insulin from sources external ofthe body, such as through a catheter inserted into the fatty tissue ofthe body, suffer from a number of limitations which include; inabilityto automate, inability for real time measurement and tracking, inabilityfor measurement and delivery on the move, inability for continuous orprogrammed delivery of insulin in a manner specific to the individual,in ability to relate diet and exercise in real time to the levels ofblood glucose in the body and the external augmentation from insulinsources external to the human body, lack of real time access tocomputational, communication and command capabilities using a mobiledevice and the software and databases resident therein, lack of realtime access to remote servers and other devices by wired or wirelessmeans to leverage the processing, storage, database and informationcapabilities resident therein; and other limitations.

The drug delivery including insulin delivery pumps of the prior art arenot intelligent and suffer from a number of limitations includinginability to wirelessly communicate and relate the drug delivery needsof the body with a number of other factors such as the ingestion of foodand physical activity for comprehensive real time control.

Additionally, the non invasive methods of the prior art such asinhalation devices and skin patches are passive methods with no commandand control capabilities and of course also lack the communicationcapabilities with information sources and servers external of theinhalation device, skin patch and other devices thus rendering thedelivery of the drug in accurate and independent of valuable collateralinformation such as the ingestion of food and physical activity. Inaddition, the prior art does not teach intelligent active skin patchdrug delivery systems or intelligent inhalation devices for drugdelivery in a controlled and safe manner in conjunction with a host ofother relevant information including other health risk factors andgastronomic information.

The prior art additionally does not teach intelligent pain managementappliances that can deliver drugs for pain management through cathetermeans, deliver drugs through skin patch means including delivery throughintelligent active skin patches that control drug delivery bystimulating the skin with mechanical, electrical, ultrasound and othermeans, and do not teach the means for pain management in conjunctionwith simply providing external stimuli such as electrical pulses/shockand other methods without an associated drug delivery by skin patch orcatheter means and further do not teach the means for communication,command and control of intelligent pain management appliances applied atone or more locations of an organ or body locations. The presentdisclosure teaches the means for pain management by using intelligentpain management appliances that have wired or wireless communicationcapabilities with a mobile device and one or more servers. The presentdisclosure also teaches the adaptation of the intelligent skin patchesthat deliver drugs for different types of pain management applicationsin a standalone manner or in conjunction with a wearable mobile deviceincluding a cellular telephone mobile device.

The present disclosure with specific references to diabetes, bloodglucose levels and insulin and the measurement, monitoring and deliverysystems thereof is intended to cover a broad range of a number of otherhealth problems and other drugs and is not to be construed as beinglimited to the specific applications disclosed herein.

SUMMARY OF THE INVENTION

The present application enables mobile devices such as cellulartelephones, PDAs, laptop computers and other devices to perform theadditional functions of measurement, monitoring and drug delivery for anumber of conditions including diabetes. Additionally, a new class ofmobile intelligent appliances specifically designed for measurement,monitoring and or drug delivery is disclosed wherein drug delivery,including insulin delivery is by means of a catheter and an externalintelligent drug pump appliance; by inhalation of drug/insulin deliverymethods and through non invasive methods for diabetes and otherapplications through intelligent skin patches and intelligent activeskin patches. In addition, various methods for pain management inconjunction with different configurations of intelligent appliances andintelligent skin patch systems are disclosed in the present invention.

Ingestion of certain foods, medications and other material such asalcohol, tobacco and non-prescription drugs has a significant bearing onthe onset of diabetes in an individual in conjunction withuncontrollable factors such as genetic predisposition. In addition, asignificant body of evidence suggests that imbalance of diet,medications, smoking, prescription/non prescription drugs, physicalactivities, occupational activities, environmental factors, stress andother high risk behavior often have a correlation to the physical andmental health of an individual.

The present invention teaches novel methods and appliances to solvevarious personal health management problems not addressed in the priorart. Various important objectives of the present invention areenumerated in detail below. Other objectives may become apparent tothose knowledgeable in the art and the invention is not to be construedas limited to the specific objectives enumerated herein:

A. Intelligent Personal Health Management Appliances for Blood GlucoseMonitoring, Tracking and Real Time Data Analysis:

The incidence of diabetes is significant in adults and juveniles and canbe related to the different types of foods ingested and physicalactivity. There is a real need for controlling the blood sugar level, anindicator of diabetes for maintaining good health. In ability to controlthe blood sugar levels at times causes diabetic shock, coma or evendeath. Diabetes is generally exacerbated by excessive body weight. Bodyweight and blood glucose are controllable by diet. Certain individualswith diabetes are prone to loss of activity in limbs such as toes andconsequently certain physical activity that leads to injury is notrecommended while safe/controlled physical exercise is advisable.Certain individuals are prone to hypoglycemia and require the quickingestion of suaar. Therefore, there is a need for an intelligentappliance that is mobile, has significant processing, storage anddatabase capabilities for measuring, monitoring and controlling bloodglucose levels in real time.

1. An objective of the present invention is a wired/wireless bloodglucose measurement appliance with the ability for the measurement ofblood glucose levels at selected times/time intervals, the tracking ofthe measured data, the comparison of the measured data with priorhistory and the correlation of the blood glucose levels with differenttypes of foods ingested and other activities. The blood glucosemeasurement appliance having the ability for acquiring a sample, formaking a measurement, for processing/storing of the software andinformation in the unit itself, in a server or a combination of the unitand the server. An intelligent blood sugar monitoring appliance that cancommunicate wirelessly is not available in the prior art.

2. Another objective of the present invention is the capability forconfiguring a mobile device such a cell phone, a PDA and other mobiledevices for the additional functions of a blood glucose measurement,wherein the mobile device acquires a blood sample, analyses the bloodfor sugar levels and performs said functions in a standalone manner orin conjunction with a local, central and network server. Additionally,the ability to correlate in real time, the measured blood glucose levelswith one or more other data such as the medications ingested, foodingested and different types of activities is enabled.

3. A system for blood glucose measurement and tracking in conjunctionwith a RF ID Tag, including reading information from the RF ID Tag andwriting information onto the RF ID Tag in real time or at selectedtimes; further having the capability to use the RF ID Tag and the mobiledevice individually or together for personal health records andinformation tracking.

B. Insulin/Drug Delivery System:

4. An objective of the present invention is an intelligent pump fordelivery of insulin and other drugs in real time or at selected timesincluding in conjunction with various activities of the individualincluding food ingestion.

5. An objective of the invention is an intelligent drug delivery pumpthat operates manually or automatically in conjunction with otherintelligent appliances including mobile devices and servers via wired orwireless communication.

6. An objective of the present invention is a specifically designedinsulin/dnig delivery pump having measurement, monitoring and trackingcapabilities.

7. An objective of the present invention is to enable a mobile devicesuch as a cellular telephone, PDA and other mobile devices to performthe additional functions of an intelligent insulin pump; further havingthe capability for wired or wireless networking with other peripheraldevices and servers for information and authentication.

8. An objective of the present invention is to track the blood glucoseand other health parameters for infusion of insulin/drug in accordancewith the infusion protocols best suited for the individual.

9. An object of the present invention is to correlate the infusionprotocols to geographical location for optimal treatment of the personalhealth of the individual such as in conjunction with a GPSsystem/server.

10. An object of the present invention is to enable reservoir/cartridgeand other mechanisms for infusion of different types of insulin bestsuited for the condition of the individual including an emergencycondition.

Drug Delivery by Inhalation:

11. An object of the present invention is a specially designedintelligent drug/insulin delivery system that is wearable/portable andhas wired or wireless networking capabilities.

12. An object of the present invention is to enable a mobile device suchas a cellular telephone, PDA and other devices for performing theadditional functions of drug/insulin delivery by inhalation methods.

13. An object of the present invention is a drug/insulin delivery systemcombining other features such as blood glucose and other parameteranalysis and monitoring/tracking. Drug/insulin delivery throughintelligent skin patches:

14. An objective of the present invention is a wired or wirelessnetworked intelligent skin patch system for controlled delivery ofinsulin and other drugs in accordance with drug infusion protocols bestsuited for the individual in conjunction with other collateralinformation such as gastronomic information.

15. An object of the present invention is to provide the user thecapability to use the skin patch delivery system or the catheterdelivery system or both in selected combinations at a selected timebased on factors that are specific to the individual.

16. An object of the present invention is an intelligent activated skinpatch system that modulates the drug/insulin delivery by one or moreskin activation/deactivation methods.

17. An object of the present invention is to enable a skin patch systemto operate in a self replenishing mode for continuous use.

18. An object of the present invention is an intelligent skin patchsystem that maintains a selected concentration level for optimaldelivery of the selected drug.

19. An object of the present invention is to enable the delivery of oneor more same or different drugs through a skin patch system.

20. An object of the present invention is an intelligent skin patchsystem configured with a plurality of reservoirs/cartridges for deliveryof one or more drugs in a controlled manner.

21. An object of the present invention is an intelligent skin patchsystem that is controlled for factors such as temperature, humidity andother factors.

22. An object of the present invention is to enable the intelligent skinpatch system for disposable or multiple repeated uses in conjunctionwith disposable or refillable reservoirs/cartridges.

Pain Management Applications:

23. An object of the present invention is to use the intelligent skinpatch system or an array of intelligent skin patch systems for painmanagement at one or more body locations/organs

24. An object of the present invention is to enable the intelligent skinpatch system to be activated by one or more methods includingelectrical, vibration, ultrasound and other methods for providingstimuli to alleviate the pain.

25. An object of the present invention is to enable the delivery of painkilling/pain alleviating medications/drugs through the intelligent skinpatch system by one or more methods such as through the skin or by thecatheter.

26. An object of the present invention is to enable the user toaccurately describe and record various types of pain and the bodylocations/organs that cause the pain.

27. An object of the present invention is to enable the individual toview a standardized body location/organ and to view the organ from oneor more angles and perspectives for accurately pin pointing the pain andfurther annotating the display with the description of the pain andother information.

28. An object of the present invention is to enable the individual toview a personalized body location/organ and to view the organ from oneor more angles and perspectives for accurately pin pointing the pain andfurther annotating the display with the description of the pain andother information.

29. An object of the present invention is to enable the tracking of painand relating said pain to one or more factors.

Real Time Measurement, Monitoring, Tracking and Analysis:

30. An object of the present invention is to enable informationacquirement by one or more intelligent appliances and enable saidinformation to be archived in one or more data bases locally or acrossthe network for personalized tracking and analysis or for collaborativeuse with permitted/authorized individuals such as health care providers.The authentication and other functions being performed per userrequirements locally on the selected appliance/device or in conjunctionswith a server such as a central or escrow server on which saidinformation is securely maintained.

31. An object of the present invention is to enable the user to carrywith him/her in wearable or portable format pertinent information foroptimal personal health management at any location or at any timeincluding in conjunction with a RF ID Tag, a mobile device, anintelligent personal health management appliance and one or moreservers.

Other objects, features and advantages of the present invention willbecome apparent from the following detailed description when taken inconjunction with the accompanying drawings.

BRIEF DESCRIPTION OF THE EMBODIMENTS OF THE INVENTION

The accompanying drawings, which are incorporated in and form a part ofthis specification, illustrate embodiments of the invention and,together with the description, serve to explain the principles of theinvention:

FIG. 1 shows a blood glucose measurement and monitoring appliance, a RFID Tag identifying the user and a mobile device associated with a userin a wired or wireless networking environment.

FIG. 2 shows a blood glucose measurement, monitoring and insulin/drugdelivery appliance that is automatic or manual wherein the insulin/drugis delivered by catheter means into the individual user, a RF ID Tagidentifying the user and a mobile device associated with a user in awired or wireless networking environment.

FIG. 3 shows a blood glucose measurement, monitoring and insulin/drugdelivery appliance that is automatic or manual wherein the insulin/drugis delivered by inhalation means into the individual user, a RF ID Tagidentifying the user and a mobile device associated with a user in awired or wireless networking environment.

FIG. 4 shows a blood glucose measurement, monitoring and insulin/drugdelivery appliance that is automatic or manual wherein the insulin/drugis delivered by two different skin patch means into the individual user,a RF ID Tag identifying the user and a mobile device associated with auser in a wired or wireless networking environment. The illustrationshows an intelligent activated skin patch system.

Further, the illustrations in FIG. 4 are also applicable for themanagement of pain using a catheter for delivering pain medication; anddifferent types of external stimuli such as electrical pulses/shock,ultrasound and other methods used singly or in conjunction with aselected skin patch for delivery of pain medication.

FIG. 5 shows a means for archiving and co-relating various types ofinformation that include various measured values of a health parameterrelated to the individual and the individuals other activities includinggastronomic information.

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

Reference will now be made in detail to the preferred embodiments of theinvention, examples of which are illustrated in the accompanyingdrawings. While the invention will be described in conjunction with thepreferred embodiments, it will be understood that they are not intendedto limit the invention to those embodiments. On the contrary, theinvention is intended to cover alternatives, modifications andequivalents, which may be included within the spirit and scope of theinvention as defined by the appended claims.

For example, the embodiments that follow relate to a networkingarchitecture, a system and apparatus for enabling personal healthmanagement in conjunction with different intelligent appliances that aremobile and or wireless, but are intended to include stationary units aswell, such as personal computers (PCs) and stationary intelligent andnon intelligent appliances; wherein as an illustration a non intelligentappliance is enabled with an external wireless capability and externalnetworking capability by means of attachments and other methods.

Further, the personal health management inquiry or request can be in anyform of intelligence, such as key entries from a keyboard, voice in anylanguage, graphics such as a key click on a graphic page, mouse clickson a view, or even tactile responses or depressions of a foot pedal.Required translations, such as from one language to another or from atactile entry to a voice command, are made automatically.

As another example, personal health management is enabled in conjunctionwith one or more types of information including gastronomic information,one or more personal and/or common databases, storage, processors andsoftware resident on one or more devices/servers located within thedevice itself, a local server, a central server, a network server orlocated across a network including the Internet. The architecture systemand apparatus may have other applications, for example in ahospital/institutional/professional environment, and the embodimentsdescribed herein are for illustrative purposes and are not to beconstrued as limiting the present invention.

The present invention is a personal health management system comprisingof various types of intelligent personal health management appliancesthat are designed and used for specific personal health managementapplications. The intelligent personal health management appliances areused in a standalone manner or in conjunction with various gastronomicinquiry and information systems, since the health of an individualgenerally pivots around the ingestion of food, ingestion of othersubstances, physical activities and mental activities.

The intelligent personal health management appliance is configured forthe real time acquisition of various data related to the individual,storing the acquired data within said appliance and or on a centralserver, displaying the selected information on said device or anotherdisplay device, making an information inquiry including health factorsand gastronomic factors to an information server having a personalhealth and gastronomic database. The present invention includesdisplaying a response to the inquiry related to personal health andgastronomic information from the information server/central server onthe selected display device including the intelligent personal healthmanagement appliance.

The present invention also includes sending a personal health and or agastronomic inquiry from the intelligent personal health managementappliance/display device to the information server, preparing theselected personal health/gastronomic response to said inquiry on theinformation server, and receiving the response to the inquiry from theinformation server with an intelligent personal health managementappliance and other devices that include a cellular telephone/a mobiledevice.

A preferred embodiment includes formatting the personalhealth/gastronomic response to the selected inquiry on the displaydevice, and displaying the formatted personal health gastronomicresponse to the inquiry on the display device and storing/retrievingsaid information on one or more databases located on the intelligentappliance itself, on a mobile device such as a cellular telephone,personal digital assistant, lap top computer, other mobile devices,stationary devices and one or more servers such a local server, acentral server, a network server and a escrow server.

The escrow server and or other servers securely stores personal healthand other information and provides access to the selected information toselected/permitted individuals/entities at the selected times usingpermission schemes and authentication schemes as defined by theindividual. The escrow server further provides that the underlyingpermission/authentication schemes are not generally made available andare executed by the escrow server without revealing or compromisingsensitive personal information.

In the present invention a user selecting an action to be performed bythe intelligent personal health management appliance/a mobile device ora stationary device connects to a central server/other intelligentpersonal health management appliances of the present invention by wiredor wireless means. The central server receives the request for theaction, and parses the necessary information to service theinformation/action request. Reference to the central server is intendedto include one or more other servers such a local server, a networkserver and an escrow server. Any information may be parsed, but willnormally include identification (ID) of the user, specificidentification information related to the intelligent personal healthmanagement appliance, the servers and other devices; information aboutthe selected input/output formats selected, communication protocolsselected, language, the basis or type of the action, the number ofactions desired, and any parameters that may be pertinent.

The parameters involved may include, for example, inputting a limit onthe values for a comparison, such as a limit on a selected healthparameter by itself or in relation/conjunction with other parametersincluding gastronomic parameters. As an example of a parameter, anaction related to the intended ingestion of a certain type of food mayresult in a warning upon comparison with specific health parameterspecific to the individual such as the cholesterol level.

Another preferred embodiment of the present invention includes a mobiledevice such as a cellular telephone, personal digital assistant, lap topcomputer and other mobile devices for enabling the control of one ormore intelligent personal health management appliances and servers, forinitiating a selected query/action using the user preferred input/outputmethods, displaying a response to the inquiry from the informationserver/other intelligent appliances on the display device/mobiledevice/intelligent personal health management appliance.

The preferred embodiment includes sending the inquiry from the displaydevice/mobile device to the information server. The preferred embodimentalso includes preparing a response to the inquiry on the informationserver. The mobile device is used for receiving the response to thepersonal health management inquiry from the information server with thedisplay device/mobile device. The preferred embodiment includesformatting the response to the personal health management inquiry on thedisplay device/mobile device/personal health management appliance, anddisplaying the formatted response to the personal health managementinquiry on the display device/mobile device/intelligent personal healthmanagement appliance.

In another preferred embodiment of the present invention a mobile devicesuch as a cellular telephone, PDA or other mobile communication devicesare additionally enabled for performing one or more functions of anintelligent personal health management appliance. As an example acellular telephone is enabled for performing the functions of a bloodsugar measurement/monitoring appliance for providing real time controlover the insulin levellblood sugar level of an individual, especially inconjunction with the real time ingestion of the various foods ingestedby the individual and the physical/mental activities related to theindividual.

The novel embodiments and teachings of the present invention will bemade clear in conjunction with the figures and the descriptions:

Referring now to FIG. 1, a blood glucose measurement appliance 100,specially designed for stationary/portable intelligent blood glucosemeasurement, monitoring and tracking applications is disclosed. Theintelligent personal health management glucose measurement andmonitoring appliance 100 comprises of the functional block 101consisting of the measurement mechanism, electronics, processor,storage, software, power supply including line and battery power; afunctional block 102 for enabling display, audio, video, text and data;a functional block 103 enabling different types of input/output andcontrols; and a functional block 104 consisting of applianceidentification including static IP, mobile IP, an imbedded or externallyattached RF ID and other identification methods, a transmitter/receiverand an internal antenna and or an external antenna 105. The appliance100 further comprises of a port 106 for external plug ins ofattachments/communication leads and a port 107 for inserting a bloodsample strip for enabling the analysis of the blood sugar levels of theindividual within the appliance 100 in conjunction with the bloodchemistry analysis capability of the chemical sample strip 140 on whicha blood sample is acquired by pricking the body at a selected locationof the individual 130. The appliance 100 is enabled for wired orwireless communication with mobile devices 110 other intelligentpersonal health management appliances 180, 181 and 182 and a centralserver 190, an escrow server 191, an Internet server 192, a globalpositioning GPS server 193 and a time keeping server 194 by means of thecommunication path 160. In addition the appliance 100 is enabled forcommunication with other peripheral devices such as a printer 170, anexternal display 171 and a local server 172. The communication path 160enables wired or wireless communication between differentdevices/appliances and servers by one or more communication protocolsappropriate for each specific communication. The individual 130 isuniquely identifiable by one or more methods including in conjunctionwith an external or imbedded RFID Tag 150 and a mobile device 110. Themobile device 110 further comprises of a keyboard 113, a display 116, anantenna 111, an external port 114 and a blood sugar analysis 115capability by one or more methods including in conjunction with theblood sample strip 140. The mobile device 110 in this illustration isenabled with additional capabilities and functions for executing bloodglucose measurement, monitoring and tracking. The mobile device isintended to include a cellular telephone CT, a PDA, a lap top computerand other mobile communication and computation devices. The mobiledevice has the capability for voice and data communication on one ormore channels using one or more inputs/outputs, one or moretransmitters/receivers, and one or more processors. The individual usermay select a preferred input and output for communication, command andcontrol which includes voice, speech, audio, video, graphics, photos anddata and other forms.

Illustrative Example 1 Use of the Intelligent Personal Health ManagementBlood Glucose Measurement Appliance

The appliance 100 is designed for wearable and stationary applicationsby itself. A blood sample is acquired by the individual by pricking thebody at a selected location in conjunction with a blood sampleacquisition device 140 and a chemical strip which is subsequentlyinserted into the blood glucose measurement appliance 100 such asthrough the port 107. The strip/disc is analyzed internally by the bloodglucose measurement mechanism 101. The processed data is archived withinthe appliance 100, itself such as in one or more storage media andrelated data bases. The individual 130 is enabled to input his/her ownidentification, ID, password or some other manual means to uniquelyidentify and relate the data to the specific individual. The individualis further enabled to utilize one or more selected input methods forcommand and control and also use same or different methods of outputincluding a touch screen or other display. Upon measurement at aselected time and at a selected location, the measured vales arepresented on the appliance 100 in a selected manner. Additionally, themeasured values and other information resident within the appliance 100is communicated to one or more other intelligent personal healthmanagement appliance for collaborative management of the personal healthof the individual; and also communicated to one or more servers forcollaborative and comprehensive analysis of one or more factors thatpotentially have an impact on the individuals health.

Illustrative Example 2 Use of the Intelligent Blood Glucose Appliance inConjunction with a Standard Stationary/Mobile Device

Additionally, the individual enabled with a standard stationary/mobiledevice such as a personal computer, cellular telephone, PDA, lap topcomputer and other mobile devices is enabled to communicate with theappliance 100 by wired or wireless means for the purpose of command andcontrol; and for the purpose of using the processingpower/storage/software and databases resident on the stationary/mobiledevice/servers in a collaborative manner; and for updating and sharingone or more related and unrelated databases resident therein. A specialfigure for a standard mobile device is not shown but it is inferred byreferring to the specially configure mobile device 110 that is shown inFIG. 1 The individual is identified by automatic recognition of theidentity of the mobile device by the appliance 100 for securecommunication between the appliance 100 and one or moreappliances/servers/devices.

A related factor for treatment and control of diabetes and other devicesis the ingestion of various types of food, the quantity of the foodsingested and the frequency at which certain foods are ingested. Themeasured blood glucose values are therefore enabled for co-relation witha number of other factors. The appliance 100 is intended for stationary,portable and mobile applications with the ability to communicate voice,data and other information on one or more input/output channels ofcommunication using a plurality of communication protocols.

Illustrative Example 3 Use of the Intelligent Personal Health ManagementBlood Glucose Measurement Appliance in Conjunction with a RF IDAssociated with the Individual

The RF ID 150 uniquely associated with a specific individual 130, suchas by wearable or imbedded means, comprises of the ability to readinformation from the RF ID or has the added capability for read andwrite onto the RF ID device. The appliance 100 has the ability totherefore communicate automatically with the RF ID 150 to send an alert,such that a self blood glucose test must be performed. The appliance 100also is enabled to communicate an alert to the individual 130 byvibration, audible, visible and other signaling means. The RF ID 150 isenabled for communication with other devices such as a mobilecommunication device including a cellular telephone, PDA, lap topcomputer, other personal health management devices, peripheral devicesand servers for communicating information and or receiving command andcontrol instructions.

Illustrative Example 4 Use of a Mobile Device Configured for Performingthe Additional Functions of Intelligent Blood Glucose Measurements

Mobile device such as a cellular telephone, PDA, lap top computer andother mobile/ and even stationary devices such as personal computers areenabled for performing the additional functions of blood glucosemeasurement and monitoring. Such a specifically configured mobile device110 has the additional capability for the insertion of a blood samplestrip 140, through a port 116 wherein the blood glucose analysis module115 measures the specific blood glucose levels for archival within thedatabase of the mobile device itself or for communication to one or moreother intelligent personal health management appliances 180, 181, 182,servers 190, 191, 192, 193, 194 and 172 and peripheral devices such asexternal display 171/printers 170 and the RFID Tag 150. In thisillustrative embodiment of the present invention one single mobiledevice performs communication, computation, command, control andmeasurement/monitoring tasks related to a specific health factor such asdiabetes/blood sugar measurement or one or more other personal healthfactors and their respective measurement/monitoring tasks.

Referring now to FIG. 2, the individual 200 is central to the system andrepresents the person seeking to manage one or more aspects of his/herown personal health including the means for obtaining information, formanaging the information and for taking the selected action at theselected time. The individual is enabled for uniquely identifyinghimself/herself by a plurality of input/output means including voice,speech and text in one or more languages, a unique user ID number, aunique password, biometric methods and other methods. The biometricauthentication information related to the individual is maintained bythe intelligent appliance 200, by the mobile device 220, the RF ID Tag250, the central server 290 and the escrow server 291 and otherdevices/servers to enable a layered secure authentication system whereinone or more specific authentication information is separated from otherauthentication information to thwart identity theft or unauthorized use.

While FIG. 1 of the present invention teaches a measurement andmonitoring system only, however, there is a need for an intelligent drugdelivery system/pump for the treatment of diabetes and other healthconditions. FIG. 2, addresses this need for controlled and real timedrug delivery by teaching in a preferred embodiment of the presentinvention, an intelligent drug delivery system with specific focus oninsulin delivery for the treatment of diabetes. However, the drugdelivery systems of the present invention are equally applicable byextension for other types of drug deliveries for various other healthconditions.

Referring to FIG. 2 in detail, an appliance 200 for blood glucosemeasurement, monitoring and insulin delivery comprises of an intelligentappliance for personal health management, drug delivery, monitoring andmeasurement. The appliance 200 comprises of a functional block 201performing the functions of a blood glucose measurement mechanism,electronics, processor, storage, software and battery/line power; afunctional block 202 consisting of means for display, audio, video, textand data; a functional block for input/output and controls; a functionalblock 204 for appliance identification, user identification,transmitter/receiver and antenna. The reference to said functionalblocks is for illustrative purposes and those knowledgeable in the artmay organize the essential functions in one or more ways using one ormore functional blocks and electrical, electronics and mechanicalcomponents and subsystems. In addition the appliance 200 a drugcartridge or a drug reservoir 209, a tube 210 by which the drugcontained in the reservoir/cartridge flows to the catheter port CP 213via a control one way check valve 211. The one way control check valveensures that the drug, which in the case of diabetes treatment isinsulin, does not flow in the reverse direction back into thecartridge/reservoir to limit contamination of the contents of thecartridge/reservoir.

The cartridge/reservoir is enabled for manual infusion by selecting themanual M 216 option by the individual 230 for delivery/infusion of thedrug/insulin by the movement of a plunger 208 such that the drug isreleased from the cartridge/reservoir in graduated quantities into thetube 210 and subsequently sent via the valve 211 and the catheter port213 to the catheter 215 containing an external needle/soft canula, whichis not shown in where in said needle/canula is inserted into the fattytissue of the individual in a selected location of the body such thatthe drug/insulin passes into the blood stream of the individual 230 in acontrolled manner. In a similar manner, the individual 230 may selectthe automatic option A 218 wherein a micro motor contained within thefunctional block is actuated by electrical signals delivered through thecommunication path 219, for enabling the controlled movement of theplunger 208 for delivery of the drug to the catheter port via the tube210 and the valve 211. Alternately, the automatic selection enables thecontrolled opening and closing of the valve 211.

Additionally, the appliance 200 is provided with a port 206 for pluggingin peripheral leads/appliance; and a port 207 for the insertion of ablood sample acquisition BSA strip 214. The appliance 200 is enabled forwired or wireless communication with servers 272, 290, 291, 292, 293,and 294; and other intelligent personal health management appliances280, 281 and 282; and one or more peripheral equipment 270 and 271; anda mobile device 220 and an RF ID Tag 250 associated with the individual230 via the communication path 260 using one or more communicationprotocols, one or more processors, one or more antennas and one or moreinput and output ports.

The mobile device 220 may be a standard communication and or computationrelated mobile device or a specifically configured mobile device forperforming one or more of the additional functions enumerated for theappliance 200. Thus the appliance 200 is enabled for operation in astandalone manner or in conjunction with a standard mobile device or amobile device configured for performing the additional functions ofmeasuring, monitoring and drug delivery. The mobile device 220 comprisesof communication, computation, command and control capabilities forvoice and data information using one or more communication protocols bymeans of a keyboard and display and related features. Optionally, themobile device 220 is configured with a blood glucose analysis or otheranalysis capabilities including drug delivery capabilities.

Illustrative Example 5 Use of an Intelligent Insulin Drug Delivery PumpAppliance

Referring once again to FIG. 2, the intelligent appliance 200 performsthe measurement, monitoring and insulin pump functions in conjunctionwith the individual 230 and the individual's requirements. Theindividual 230 measures his/her blood glucose level by pricking thebody, acquiring a blood sample on a blood sample strip and subsequentlyinserting said sample strip into the port 207 of the appliance 200;wherein the blood glucose level is analyzed automatically and theresults compared against a preset value for one or more selected orautomatic actions. The measured value/results are alsopresented/displayed for review by the individual 230 and stored withinthe database of the device and/or communicated externally of theappliance 200.

Upon determination by the individual that the measured values of theblood glucose levels warrant the infusion of a selected amount ofinsulin into the individual 230's body, the individual activates themanual mechanism M 216 and plunger 208 to infuse/inject a controlledamount of insulin into the body. The quantity and time at which theinsulin was injected is stored by manual input or automatic input meansin a database within the appliance 200 or in other databases external ofthe appliance 200. The individual 230 is enabled to relate the amount ofand the types of foods ingested to the measured blood glucose values toinfuse the recommended/selected amount of insulin into the body. Thusthe individual is able to regulate in real time the insulin levelswithin the body for dynamic diabetes management.

Alternately, the measured blood glucose levels are automaticallycompared within preset values for determining the infusion levels ofinsulin best suited for the individual and his/her infusion protocolestablished in conjunction with selected health professionals andhistoric and contemporaneous information related thereto includinggastronomic information, blood pressure, ECG and other information. Theselected amount of insulin in accordance with the preset insulininjection protocols or manually selected protocols is automaticallyinjected by mechanism A 218 which receives a signal for graduatedmovement of the plunger 208 and or the graduated opening of the checkvalve 211 ensuring that the selected/prescribed qty of insulin isinjected at the selected time. The quantity of insulin infused and thetime at which it was infused is automatically recorded in one or moredatabases including within the appliance 200, a mobile device 220, a RFID Tag 250 and one or more other intelligent personal health managementappliances 280, 281 and 282 and servers 272, 290, 291, 292.

The geographical location at which the insulin infusion was effected isaccurately determined in conjunction with a global positioningcapability/GPS server and the accurate time at which the infusion waseffected is also recorded in conjunction with built-in time keepingcapabilities of the appliance 200 or the mobile device 220 or a timekeeping server 294. The change in blood glucose levels and itsrelationship to gastronomic and other information, the amount ofinfusion of insulin, the frequency of infusion of insulin and otherfactors are co-relatable in the time domain including geographicalposition domain and with other personal health risk factors enabling theindividual to proactively manage his/her personal health wherever he/shemay be and in whatever time zone they may be.

In addition, one or more reservoirs/cartridges of insulin are enabledoptionally within the appliance 200, such that the infusion of fastacting, slow acting and other types of specially formulated insulininfusions are enabled for one or more conditions including an emergencycondition such as diabetic shock, coma and other life threateningconditions. Further the appliance 200 is enabled to communicate manuallyor automatically to certain preset alarm levels and hazard levels toactivate one or more user selected emergency protocols.

Illustrative Example 6 Use of an Intelligent Insulin Drug Delivery PumpAppliance in Conjunction with a Standard or Specially Configured MobileDevice

A mobile device such as a cellular telephone, PDA and other mobiledevices are enabled to communicate in a proximate communication modewith the wearable intelligent pump appliance 200. The communication,computation, command and control capabilities of the mobile device areleveraged by the intelligent pump appliance 200 to enable enhancedprocessing, storage, software and database capabilities. Similarly, thecapabilities of one or more servers are utilized by the intelligent pumpappliance 200. In addition, the RF ID Tag 250 is used to read from andor write to information in real time thus providing real timeinformation via the appliance 200 itself, via the mobile device itself,via the RF ID Tag itself, via one or more remote appliances/servers or acombination thereof.

Referring now to FIG. 3 in detail, the ability to deliver drugs throughthe an inhalation method through nasal passages and the mouth/throat iswell known. However, the drug delivery systems consist of spraying adrug substance in an uncontrolled manner through an apparatus that doesnot provide a means for manually or automatically recording and trackingthe amount, frequency and time at which the drug was delivered by thesemeans and further does not enable the drug infusion by inhalationmethods to other health factors including gastronomic factors.

A number of preferred embodiments of the present invention overcome thelimitations of the prior art inhalation techniques. This is explained indetail by referring to FIG. 3 and the descriptions disclosed herein:

A specifically designed intelligent appliance for delivery ofinsulin/other drugs 300 comprises of a functional block for electronics,processor, storage, software, battery and or line power 301 whereinfunctional block representation 301 may optionally consist of a bloodglucose analysis, BGA capability as indicated in appliance 300, afunctional block 302 for enabling different types of inputs/outputs andcontrols; a functional block 303 comprising of display including touchscreen display, audio, video, text and data capabilities; a functionalblock 304 comprising of a valve mechanism 311 for enabling one way flowof the drug/insulin for inhalation by the individual 330 wherein thedrug flow is enabled including means for measuring volume, pressure,quantity, and the duration for which the drug was delivered and the timeat which the drug was inhaled by a specific individual 330; a functionalblock 306 comprising an antenna, a transmitter/receiver, the antennashown externally as 305; and a functional block 307 consisting of andrug/insulin reservoir or a replaceable/refillable cartridge including ameans for manual delivery by injection/depression of a plunger 313 suchthat the drug/insulin is delivered manually in controlled amounts viathe valve 312 or by automatic means by a motorized valve or other means314. The drug/insulin is inhaled by the individual upon manual orautomatic selection by the inhalation tube 310 which is directlyinserted into the mouth for delivery to the mucosal walls of the mouth,throat and nose. Alternately the tube 310 with a facial mask, which isnot shown enables controlled inhalation via the nose only, via the mouthonly or a combination of both. The appliance 300 further comprises of aport 308 for external plug in purposes. The appliance 300 is enabled forwired or wireless communication by the communication path 360 using oneor more input/output channels and one or more communication protocols onone or more selected channels.

In an alternate configuration, not shown, the appliance 300 is enabledwith a blood glucose or other health parameter definition capability fordetermining the level of or dosage of the drug to be inhaled.

Once again referring to FIG. 3, the individual 330 is enabled foridentification by manual input for authentication and or actuation ofthe appliance 300. The individual in another embodiment is enabled forauthentication and actuation of the appliance 300 by RF ID Tag 350 ormobile device means. The RF ID Tag is readable and or writeable. TheRFID Tag contains individual specific information that is preloaded andor periodically updated securely. One or more user selected biometricauthentication methods are enabled for operation of theappliances/devices/server and software and database contained therein.The appliance 300, the RF ID Tag 350 and the mobile device 320 areenabled for wired or wireless communication with peripheral devices suchas a printer 370, a local server 372, an external display 371; one ormore other intelligent personal health management appliances 380, 381and 382; a central server 390, an escrow server 391 on which secureinformation may be maintained, an Internet server 392 and a GPS server393 and even a time keeping server not shown.

The mobile device 320 may be a standard mobile device not enabled forany health parameter measurement or alternately a specially configuredmobile device 320 shown with a blood glucose measurement capability 320or other health parameter capability. The mobile device 320 is enabledfor one or more types of input/output including a keyboard input, adisplay including a touch screen display. The mobile device 320 may be acellular telephone CT or a mobile device MD including a lap topcomputer, a PDA and other communication, computation and controldevices. By inference the references to the mobile device or intended toinclude a stationary device performing one or more similar functions ofthe mobile device. The blood sample acquisition tool 315 enables a bloodsample to be acquired by pricking the selected area of the body of theindividual 330 for subsequent insertion and analysis within theappliance 300 or the mobile device 320 for blood sugar determination andthe need for insulin inhalation. By inference the BSA 315 function isintended for the acquisition of other types of samples for other typesof health analysis and for inhalation of the appropriate drug substance.

Illustrative Example 7 Use of a Specifically Designed IntelligentAppliance for Delivery of Drugs/Insulin by Inhalation

The individual 330 acquires a sample of blood by pricking his/her bodyat a selected location wherein optionally the sampling may be automatedby enabling the pricking action to be automated, drawing a sample ofblood onto a strip, in this present invention, the reference to thestrip is intended to include all other forms such as strips, disks,palettes and other methods that enable the sample of blood to beacquired onto a passive or active chemical media which subsequentlyenables the blood sugar/glucose level to be measured by a blood glucosemeasuring mechanism by manual and or automatic means. The individualdetermines his/her blood glucose level in conjunction with theintelligent blood glucose measurement capability built into appliance300 or an external blood glucose measurement meter such as the mobiledevice CT/MD 320 which may be enabled with a blood glucose analysiscapability. Upon determination manually or automatically in conjunctionwith the appliance 300 or the CT/MD 320 that the blood glucose levelmandates the infusion of insulin of a selected level, the individual 330inhales the insulin through the tube 310 into the mouth or the nose. Theinhalation of the insulin is controlled by the check valve 311 and theamount of insulin released from the reservoir/cartridge 307 iscontrolled manually by depressing the plunger 313 or a similar mechanismvia valve 312 or enabled automatically in conjunction with a motor orother metered release mechanism M 314. The amount, rate, flow, pressure,duration and other insulin inhalation parameters are measured andrecorded onto a local storage within the appliance 300 and orcommunicated externally of the appliance 300 to other intelligentappliances, mobile devices, printers, displays and servers forcontemporaneous use or use at a selected time in conjunction with otherpersonal health information including gastronomic information. Theinput/output may be in any form of intelligence selected by the user.The information and measured blood glucose values and the amount ofinsulin inhaled and other parameters are archived locally and orexternally including in a mobile device that is proximately present withthe individual 330.

Example 8 Use of a Mobile Device CT/MD that is Configured with a BloodGlucose Analysis Capability and an Insulin Inhalation Capability

Alternately, the user 300 is enabled to use the standard CT/MD 320 forenabling pass through communication in conjunction with the appliance300, for storage/retrieval of data contained within the mobile deviceand for other health management functions to augment the capabilities ofthe intelligent insulin inhalation appliance 300. In another preferredembodiment of the present invention, a mobile device such as a cellulartelephone, PDA and other devices are configured with the additionalcapabilities for blood glucose analysis and inhalation capabilitiescontained therein. The user 330 utilizes the CT/MD 320 in a mannersimilar to the functioning of the intelligent appliance 300 and isenabled to perform one or more other functions contemporaneously orsequentially on one or more input/output channels using one or moreselected communication protocols. The RFID Tag 350 is enabled for useindependently or in conjunction with the mobile device 320 and or theintelligent inhalation appliance 300. Other control, storage andauthentication tasks may be performed independently by the intelligentappliance 300 or the CT/MD 320 or in conjunction with the processing,storage, software capabilities of one or more other appliances/devicesand servers.

The illustration of the insulin inhalation appliance 300 and the CT/MD320 configured with BGA and insulin inhalation capabilities was withspecific reference to the inhalation of insulin but is intended to beapplicable for other drugs/medications and is not to be construed aslimiting to the illustrated examples.

Another novel embodiment of the present invention is an intelligentinsulin/drug skin patch. It is well known that drugs/medications passthrough the skin and the fatty tissue into the blood stream ofindividuals.

Prior art technology enables a skin patch that has a coating of theintended drug, the application of said skin patch to the skin of theuser at a selected location and ultimately the reliance on the assumedrate at which the drug diffuses out of the patch into the skin and theninto the blood stream. In the prior art, the number of parameters thatrelate to this diffusion of the drug out of the skin patch into theblood stream are not controlled in real time and are totally dependenton static models derived from a number of individuals and may have norelevance to the specific individual or his/her personal health factors.

Consequently there is a need for an improved intelligent skin patch forcontrolled and optimal delivery of drugs through the skin based ondynamic needs and specifically suited for the individual. The presentinvention embodies and teaches two different intelligent skin patches.Other variations and configurations thereof can be made by thoseknowledgeable in the art in conjunction with the teachings of thepresent invention and the invention is not to be construed as beinglimited to the illustrations presented herein.

1. Intelligent Skin Patch System:

Referring now to FIG. 4 in detail, an intelligent skin patch system 420is described in detail. The intelligent skin patch is affixed to theskin by adhesives or enabled additionally to be strapped on by beltmechanism for secure and continuous contact of the skin patch with theindividual's skin. The intelligent skin patch appliance 420 comprises ofan insulin skin patch 425, shown with grid marks for highlighting thedrawing, providing contrast for illustrative purposes, which makescontact with the skin 426. The case of the appliance 420 furthercomprises of transmitter/receiver, antenna 432, appliance ID, processor,storage, software, electronics, mechanism together illustrated as 421; acartridge/reservoir 430 with a manual plunger 431, a valve 429 throughwhich insulin or other drugs are enabled for delivery via the tube 428to the distributor 424 which evenly spreads the drug over the entiresurface area of the skin patch 425. A battery 423 is shown for internalpower supply. It should be understood that the external power supply notshown but is enabled by inference. The communication bus betweendifferent components within the intelligent skin patch 420 is shown as422. This bus may be wired or wireless.

For enabling automatic release of insulin from the reservoir to the skinpatch a micro motor M 427 or other automated means is enabled inconjunction with a valve 429 or other controlled metering mechanism. Thesystem 420 is enabled simply as a skin patch with a reservoir and nomanual plunger capability or with a manual plunger capability included.The illustration shows a cartridge/reservoir with a plunger but theoption without a manual plunger is inferred.

Alternately for manual release of the insulin to the skin patch aplunger that forces insulin out of the cartridge/reservoir 430 isenabled. This novel design and system of the present invention fordelivery of insulin and other drugs via the skin patch is unique and isnot available in the prior art. This system in the present invention isreferred to as intelligent skin patch system since there is no provisionin this configuration to stimulate the skin.

Example 9 Use of the Intelligent Skin Patch System in Conjunction with aBlood Glucose Testing Appliance/Monitor

Referring once again to FIG. 4, the individual 470 determines at aselected time his/her blood glucose level in conjunction with a standardblood glucose measurement/monitor device [not shown] or an intelligentblood glucose appliance 400. The appliance 400 is similar to theintelligent blood glucose measurement/monitoring appliances illustratedin prior figures FIG. 2 and FIG. 3 and for reasons of brevity it neednot be described in detail. The appliance 400 is used in conjunctionwith the acquisition of a blood sample via the BSA 472 or other means.

Upon determination that the measured values of the individual warrantthe infusion of insulin from external sources, the individual choosesthe skin patch method and applies the intelligent skin patch system 420that has been described in detail above. The system 420 may be held tothe skin with an adhesive, such adhesive being part of the skin patch,or applied separately. This adhesive ensures that the skin patch is heldin intimate contact across its entire surface to the skin of theindividual 470. Alternately, the system may additionally be strapped tothe skin by means of a belt or other mechanism for secure and continuouscontact with the skin and continuous infusion of insulin to the bloodstream by infusion via the skin/fatty tissue.

The intelligent blood glucose appliance 400 may provide the bloodglucose measured values to the individual by visual, voice or otherintelligence means for the individual 470 to initiate the application ofthe system 420 to the skin and activate the system 420; or the systemmay be strapped on at the outset to the individual at a selected bodylocation and the intelligence is automatically provided from theappliance 400 to the intelligence skin patch system 420 for activationof the system 420 and the initiation of the delivery of insulin throughthe system 420.

As an example, in the event the measured blood glucose level is higherthan a preset value then the appliance 400 transmits a wired or wirelesscommunication signal to the intelligent skin patch system 420 for acontrolled release of insulin best suited for the individual and his/herspecific protocols or for a standardized release of insulin inconjunction with normalized insulin delivery protocols for an individualof that type of demographics such as age, sex and other factors. Thesignal sent from the appliance 400 is received by the antenna 432, andthe receiver, the transmitting appliance 400 and the system 420 areenabled for recognition by their identification ID to ensure that thecorrect instructions are being provided to the intended system 420 fromthe appliance 400. Similarly, a cellular telephone, PDA, lap topcomputer and other mobile devices represented by 410 are enabled forcommand and control or alternately for command and control inclusive ofblood glucose measurement and monitoring capabilities. The individual'shealth profile and individual specific information including insulininfusion protocols are enabled within the appliance 400 or the mobiledevice 410 either of which may be used by the individual 470 inconjunction with the intelligent skin patch system. Additionally,certain selected individual specific health information and insulininfusion protocols are enabled within the skin patch system 420 andenabled for operation with its processor, storage, software and othercapabilities. Thus the intelligent skin patch system operates inconjunction with a specifically designed intelligent blood glucosemeasurement and monitoring appliance 400, a mobile device 410, a RF IDTag 473 which is enabled for reading information from and or writinginformation to; one or more servers 490, 491, 492, 493 and 494, and oneor more intelligent appliances 483, 484 and 485, a local server 482,external display 481 and a printer 480. The communication between theenumerated servers, devices and intelligent appliances is enabled by oneor more wired or wireless communication paths using one or morecommunication protocols as represented by the communication path 460.The intelligent skin patch system thus is enabled for operation usingits own processing, storage, software, data base wired/wirelesscommunication capabilities or in conjunction with the processing,storage, database, software and wired/wireless communicationcapabilities resident within an intelligent appliance 400, a mobiledevice 410, one or more servers including time keeping, globalpositioning and other servers for delivery of insulin to the individualat the selected time and in a selected geographical location in selecteddosages that are specific to the individual. Further the intelligentskin patch system 420 is thus able to communicate/interact for variousforms of information and intelligence such that the delivery of insulinis coordinated in conjunction with collateral information that includesgastronomic information [gastronomic factors such as the types of foodsingested and the times at which the foods are ingested may havesignificant impact on the production of insulin by the body and theamount of insulin needed at any given time by the body]. The intelligentskin patch system of the present invention is novel and has simificantutility further having real time communication and control capabilitiesand for synergistically operating with information contained within orexternal of the system. Prior art systems have no forms of intelligenceor any communication capabilities let alone real time communicationcapabilities.

The intelligent skin patch system 420 when used in the automatic mode isenabled for controlled delivery of insulin by a micro motor or otherdelivery mechanism 427 wherein the motor 427 is controlled inconjunction with the processor and electronics contained therein.

Example 10 Use of the Intelligent Skin Patch System for the AdditionalFunction of Delivery of Insulin Through a Catheter in Conjunction withthe Skin Patch or Independent of the Skin Patch

The delivery of insulin through the skin is slower compared to thedelivery of insulin through direct infusion methods such as through acatheter that is inserted into the fatty tissue/blood stream of theindividual. At times diabetics may require a quick infusion ofsignificant and controlled quantity of insulin which is not physicallypossible through a skin patch whether the skin patch is intelligent ornot.

Therefore, in an alternate embodiment of the present invention, theintelligent skin patch system is enabled for the additional function ofdirect infusion of drugs/insulin through a catheter port [not shown],wherein the catheter port is part of the system 420 and enables anexternal catheter 471 to be attached to the catheter port of the system420. The individual 470 is enabled with a catheter 471 for delivery ofinsulin by direct infusion method such that the catheter 471 is enabledfor attachment to a catheter port of the system 420. The insulin thus isenabled to flow from the system 420 through the catheter 471 into theindividual 470. In this configuration, the individual is enabled foroperating a plunger 431 to infuse a graduated amount of insulin from thereservoir/cartridge through the catheter into the body. This additionalamount of insulin may be in lieu of or in addition to the amount ofinsulin being released slowly through the skin patch.

The intelligence of when to use the alternate method of catheterinfusion may be provided by the intelligent skin patch system which isenabled for using the measured values of the blood glucose inconjunction with a range of health parameters in a standalone manner orin communication with other servers, mobile devices and appliancesexternal of the system 420; or in the case of inability to measure andthe perception/judgment by the individual that a controlled andgraduated amount of insulin must be quickly infused in criticalsituations that diabetics often face.

Thus the novel features of the present invention enable the intelligentskin patch system to be used in a plurality of ways that include theskin patch method of drug/insulin delivery and the catheter method ofdrug/insulin delivery or a controlled combination of both methods. Theprior art does not enable such capabilities for controlled andintelligent delivery of drugs/insulin through intelligent skin patchesnor does it teach a skin patch system that has the additional dualcapability for delivery of drugs/insulin in conjunction with a catheter.

Example 10 Use of the Intelligent Skin Patch in a Self Replenishing Modeto Augment the Supply of Drugs/Insulin within the Skin Patch

Normally, skin patches are formulated with a certain predeterminedamount of drug/insulin contained therein, which at the projected rate ofdelivery and absorption through the human skin lasts for a definedlength of duration. The limitation of this static approach to drugdelivery through the skin patches is that the rate at which drugsincluding insulin are absorbed through the skin is variable and isdifferent for different individuals and their body chemistries andphysical factors. The rate of absorption is also dependent on thelocation of the body at which the skin patch is applied. Environmentalfactors such as extreme dryness/lack of humidity may also effect theevaporation/loss by other factors and the absorption through the skinsince even the physical factors related to the skin are altered by theseenvironmental and body chemistry/physical conditions. Consequently,there is a need for a skin patch that is self replenishing to providecontinuous uninterrupted delivery.

In a preferred embodiment of the present invention, the drug/insulinskin patch 425 is enabled for maintaining a selected concentration levelof the drug/insulin within the skin patch, including a constant orvariable concentration level of the drug/insulin. This novel feature isaccomplished in the present invention in conjunction with areservoir/cartridge of the drug/insulin 430 which through the valve 429and the delivery tube 428 and the distributor 424 enables a constantamount of micro drops of the drug/insulin to be delivered to the insulinskin patch 425 such that the concentration level of the drug/insulin isconstant and or at a selected concentration level. The ability tomeasure/sense the concentration level of the drug within the skin patchand to provide this information to the processor such that the valve429/motor 427 are intelligently controlled and to enable saidcommunication for control purposes is enabled by the communication path422. Consequently, a selected rate at which the drug/insulin is providedis enabled automatically with a feed back loop of a measured value ofthe dmg/insulin within the patch, a selected control value and the meansfor automatically metering a selected quantity of the drug/insulin tomaintain said selected control value. Of course, the means fordelivering the drug/insulin at a controlled metered rate withoutmeasuring the concentration value of the drug/insulin within the skinpatch is by default enabled.

In addition, the intelligent skin patch system 420 is enabled optionallyto measure humidity, temperature including skin temperature and ambienttemperature and other environmental and individual related biologicalfactors such that the rate/quantity/time/frequency at which thedrug/insulin is delivered is fine tuned to the geographical location andambient conditions in which the individual is present and specificmeasured biological parameters that are specific to the individual. Inaddition, the intelligent skin patch 420 is enabled with internalintelligence and communication capabilities such that the controlleddelivery of the drug/insulin through the skin patch and or a cathetermethod is controlled in conjunction with a number of factors thatinclude gastronomic, personal health, geographical location, internalbody parameters and external environmental parameters for comprehensivepersonal health management of the individual in real time or at selectedtimes; including in conjunction with a mobile device/stationary device.

Example 11 Use of the Intelligent Skin Patch System for RefillableApplications or Disposable Applications

The intelligent skin patch system 420 may itself be used in many ways.

1. Use the entire intelligent skin patch assembly 420 one time and atthe end of its useful life dispose of the entire system including themechanism, electronics and the skin patch; and the reservoir/cartridgein the case where this option is enabled.

2. Use the entire skin patch assembly 420 multiple times and simplychange the skin patch 425 only.

3. Use the cartridge/reservoir 430 only once and dispose of thecartridge/reservoir at selected interval of time or upon sensing theabsence or low concentrations of the drug/insulin.

4. Use the cartridge/reservoir multiple times by enabling a safe refillcapability for addition/removal of the drug/insulin, includingsanitizing the cartridge/reservoir or one or more parts of the assembly420.

5. Enable the intelligent skin patch system 420 for delivery of one ormore different drugs/different concentration of said drugs that includedifferent types of insulin such that the system 420 or parts thereof canbe used for multiple uses and the drugs/insulin delivered through theskin and or by means infusion through a catheter.

6. Enable the intelligent skin patch system 420 with multiple skinpatches that are constructed and organized such that one or more drugsare sequentially or contemporaneously delivered.

An example of a skin patch organization is concentric annular rings ofdifferent drug containing patches contained within a single larger skinpatch. Other types of skin patch organizations are possible byextension.

7. Enable an intelligent skin patch system 420 with multiple microcartridges/reservoirs where in a selected cartridge/reservoir contains aselected drug, thus enabling different drugs to be delivered through acommon skin patch or different skin patches for the individual to managemultiple personal health factors; including enabling delivery ofdifferent drugs from different cartridges/reservoirs by skin patchdelivery method and or catheter delivery method.

The above different configurations and uses of the intelligent skinpatch system as embodied in the present invention are useful, unique andnovel and not taught by the prior art. The figures appended to thisspecification including FIG. 4 readily enable the teaching of the aboveoutlined uses 1-7 and other uses and separate figures are not deemednecessary to illustrate these different configurations.

Referring once again to FIG. 4, another unique embodiment of the presentinvention is a novel variation of the intelligent skin patch system 420,specifically illustrated as an intelligent active skin patch system 440.The novel features of the intelligent active skin patch system 440include significant similarities to that of 420 but additionally includethe ability to activate the skin by a plurality of means forincreased/controlled absorption of drugs/insulin through the human skin.Of course all references to skin patches are intended in the presentinvention animals by extension.

As described in extensive detail above with reference to system 420, thehuman skin is an active entity that modulates its behavior andcharacteristics based on a number of body/individual dependent andexternal factors. The pore size of the skin is affected by cold and heatresulting in the pores closing or opening and increased blood flow ordecreased blood flow; and also affecting body temperature.

These and other factors either limit or accelerate the absorption ofvarious drugs through the skin. Thus the ability to externally controlthe behavior/characteristics of the skin provide another added controlmeans for efficient drug delivery through the skin wherein byappropriate stimulation of the skin or lack there of the rate/nature ofdelivery of a drug through the skin can be accelerated or slowed down. Anovel embodiment of the present invention is an intelligent active skinpatch system 440 that leverages the additional control capabilities fordrug delivery through a skin patch by a skin activation, SA mechanism452. The SA mechanism 452 activates the skin by one or more selectedmethods used singly or in combination. The system 440 is configured withselected skin activation methods or a combination of skin activationmethods.

These skin activation methods include:

1. Varying the temperature of the skin by applying heat or cold. As anexample heat may be generated by electrical resistance means inconjunction with the battery power source contained within intelligentskin patch system 440 [battery not shown for keeping the figure lesscluttered] and applied to the skin. Cold can be generated by blowing airacross the skin or by other methods including cryogenic means.Alternately, the temperature of the cartridge/reservoir may becontrolled to enable heating and cooling of the drug itself such thatthe skin patch and skin temperature is as a result controlled.

2. Providing controlled mechanical agitation or stimulation of the skinby a vibration or other methods wherein the mechanical vibration isenabled by the power source and other mechanisms contained within theassembly 440.

3. Providing controlled sound waves including sound waves at one or morefrequencies including ultrasound frequencies using the appropriate soundtransducers or other methods within the assembly 440 in conjunction withits electrical, electronic and mechanical, power supply and othercapabilities to activate/deactivate the skin in a controlled manner

4. Providing controlled electrical signals of various frequency,intensity, power, current and voltage such that the skin isactivated/deactivated. The internal power supply and electronics ofsystem 440 enable this capability

5. Providing optical/light source[s] of different or varyingcharacteristics and duration such that the skin isactivated/deactivated.

6. Providing one or more different methods for activation/deactivationand control of the skin used singly or in selected combinations bestsuited for the selected drug to be delivered for the selectedphysical/biological characteristics of the individual and theenvironment/geographical location that the individual is in.

Referring once again to FIG. 4, particularly intelligent active skinpatch system detail 440, the system comprises of one or more functionalblocks wherein the functional blocks are for ease of illustration andare not intended to be assumed as rigidly organized as thus, saidfunctional blocks including an antenna 446 shown externally, afunctional block 447 including a transmitter, receiver, antenna, systemID; an internal wired or wireless communication path/bus shown as 450;an external wired or wireless communication capability 460; acartridge/reservoir 444 with an optional plunger 445; a functional block441 containing software and storage; a functional block 453 consistingof processor, electronics, and mechanism; a valve mechanism 454, adelivery tube 453 or similar means for drug delivery to the skin patch449 that is internal of the assembly 440; a micro distributor 448 thatenables even delivery of the drug across the skin patch 449, the skinshown as 454 and finally the skin activation mechanism SA 452. The skinactivation mechanism in conjunction with the internal electronics,processor, mechanisms, storage, software and other capabilities deliversthe selected skin activation/deactivation methods to the skin thatinclude mechanical, vibration, sound including ultra sound, electricalimpulses and various other forms/methods delivered singly or in selectedcombinations best suited for the individual.

The system 440 is illustrated with a blood glucose analysis andmeasurement capability contained therein. However, this BGA 443capability may be optional and the blood glucose measurementcapabilities of an external intelligent appliance such as appliance 400may be used or the capabilities of a mobile device such as 410 may beused in a configuration of 440 wherein the BGA capability is not presentor in addition to it. The intelligent active skin patch system 440 mayadditionally be used in a manner as illustrated for system 420 with theoptional or additional capability for using the catheter method for drugdelivery using a catheter port [not shown] contained within the assembly440 and a catheter 471. Thus the individual 470 is enabled to use theintelligent skin patch system 420 and or the intelligent activated skinpatch system 440 in a standalone manner or in conjunction with one ormore intelligent appliances 483, 484 and 485; an external display 481, aprinter 480, a local server 482, a central server 490, an escrow server,an Internet server 492, a time keeping server 493 and a globalpositioning system/server 494 using wired or wireless communication formanaging diabetes and other personal health ailments in real time usingthe extensive personal health and other collateralinformation/capabilities resident within the individual's mobile device410, the RF ID Tag 475 and other wearable intelligent appliances such asappliance 400.

The present invention has illustrated in detail variousappliances/apparatus and systems for real time personal healthmanagement with special reference to diabetes. However, the disclosureis valid for a range of other health factors.

Example 12 Use of the Intelligent Active Skin Patch System

The operation of the intelligent active skin patch system 440 is similarto that of the intelligent skin patch system 420 except that the skin isactivated/deactivated by one or more methods in a controlled manner foroptimal drug delivery and absorption. The individual 470 having manuallydetermined that there is a need to activate the skin is enabled tochoose one or more methods such as mechanical vibration ultrasoundvibration, heat and other methods to enhance the absorption of the drugfrom the skin patch to the individual. The user is enabled to select theskin activation/deactivation method or alternately the system 440 in astandalone manner or in conjunction with another intelligentappliance/mobile device determines the parameters of the skinactivation/deactivation. The activation/deactivation and the intensity,duration and other parameters of the activation/deactivation are enabledfor determination and control in conjunction with a number of parametersrelated to the individual including gastronomic information. Theintelligent skin patch system 420 or 440 are enabled for control by theindividual locally using a selected input/output method such as voice,touch, keypad or other methods or controlled in conjunction with anexternal device such as a mobile device. Use of skin patch systems andmodified skin patch type systems for pain management:

Example 13 Use of the Intelligent Skin Patch System 420 or theIntelligent Active Skin Patch System 440 for Pain Management

Certain types of pain are controllable by infusion of selected drugs ina localized area where the pain is prevalent or by enabling the drug tobe absorbed by the blood stream through the skin for general control ofthe pain. A preferred embodiment of the present invention enables theindividual to use one or more same or different types of intelligentskin patches applied at one or more locations of the individual's bodyfor the intelligent real time management of pain wherein theappliance[s] 420/440 operates in a standalone manner or in conjunctionwith an external device such as mobile device 410 for command andcontrol tasks. There may be a series/plurality of intelligent skinpatches used at the same time for the management of the same pain,similar pain or dissimilar pains at one or more locations such that eachintelligent skin patch is controlled in conjunction with a mobiledevice/server or used independently. The information required for theselected intelligent skin patch system 420/440 to operate in a specificmanner best suited for the individual is enabled by the internalsoftware/databases of the appliance 420/440 or the mobile device inconjunction with a central server and other intelligent devices. Theinformation transmitted by the intelligent skin patch 420/440 is enabledfor use internally or in conjunction with an externaldevice/server/appliance.

Application of certain selected external stimuli such as electricalpulses/shock, ultrasound, vibration, and other methods is intended tocontrol and manage the intensity, frequency and the incidence of painexperienced by the individual using the intelligent active skin patchsystem 440. The ability of the system 440 to deliver theactivation/deactivation stimuli to the area of the pain is enabled withan optional design of 440 that does not contain a skin patch or astandard design that contains the skin patch. In addition variousfeatures such as a catheter for delivery of the drug are also optionallyenabled. The ability to provide, heat, cold, electrical pulses/shock andultrasound energy to a localized area via a method not containing a skinpatch or with a skin patch method enables the individual to control thepain by one or more selected methods. The ultrasound method may treatpain that is internal to the body and not just at skin level. Theultrasound energy may be modulated and adjusted to treat pain at theskin surface or at a selected depth from the skin for treating varioustypes of pains that are deep in the body.

Example 14 Visual Mapping of Pain in Conjunction with a Mobile Deviceand an Information Server

In another embodiment of the present invention, the level of pain, theintensity of pain, the duration of pain and the location of pain andother factors in one or more body locations and organs is enabled forbeing recorded by voice or other methods including by image, graphicsand other methods. Health care providers would like to know thesedetails to discern if the pain is life threatening or general in nature.A pain in the heart/chest cavity may be due to gas, heavy lifting or dueto a heart attack. Recording in real time or at selected time suchvaluable information related to pain is of significant value. Apreferred embodiment of the present invention is to enable theindividual to use a mobile device such as a cellular telephone, PDA, laptop computer or other devices for recording all relevant informationrelated to pain including pain related to a specific organ or differentbody locations. Said pain related information is enabled for recordingin a tabular format, look up tables or in a database format or otherformats for further relation to other factors pertaining to theindividual such as gastronomic information, exercise and other factors.In another preferred embodiment of the present invention, a twodimensional, three dimensional, cross-sectional and other views of theselected organ are presented to the individual in a display format suchas on a touch screen such that the individual can with accuracy pinpoint the source[s] of pain for informed recording in a database and forreal time communication or communication at a selected time with trainedhealth professionals. In another preferred embodiment of the presentinvention, the individual may select one or more icons to indicate thenature of the pain for ease of description, recording and communication.

Certain pains may radiate out from a center point, certain pains mayradiate in from the periphery, certain pains may be pulsating and otherpains may have descriptions that are not easily describable with planaror three dimensional geometric representations such as dull pain, athrobbing pain, a steady pain and other subjective but valuabledescriptions. However, the present invention enables the individual toselect certain pre defined geometric patterns that describe the specificnature of pain or define customized pain icons that are specific to theindividual or use predefined/customized word descriptors.

As a specific example, the individual experiencing pain in theintestinal tract may communicate via the mobile device 410 with aninformation server that provides a two or three dimensional graphicsimage of a standard human intestinal tract on the display of theindividual's mobile device/stationary device. The individual is enabledto rotate or otherwise manipulate the graphics image of to locate anarea that he/she can select by touch sensitive means to exactly pinpoint the location of the pain and further select one or more othericons that indicate different types of pain patterns. Thus enabling theindividual to accurately record various pain symptoms including by voicemeans and precisely communicate them to a trained health professional.

Pain Management with Visualization of Body Locations and OrgansExhibiting Pain:

Example 15 Pain Management in Conjunction with Visualization of Organs

Another specific example is the visualization of the heart in threedimensions and the ability to rotate/slice and other wise manipulate theimage of the heart for recording/annotating the pain felt by theindividual at one or more locations in the selected organ or bodylocations. Similarly other organs may be visualized for determining painaccurately. The nature of the pain, the location of the pain and therelationship of the pain to a time line wherein other related activitiessuch as food ingestion have taken place enables the individual todetermine whether the pain warrants emergency response or response at alater time/selected time or is worth ignoring. Pain and its occurrencemay have certain patterns which are therefore co-relatable with otherfactors. For example certain people suffer from migraine headaches butnot all their headaches are happenstance, they are in some cases relatedto the ingestion of foods such as chocolates, coffee and other factors.

Thus the present invention enables the individual to accurately trackpain, describe pain, visualize pain in one or more graphical images ofspecific organs/body locations and relate their pain to a number offactors in real time or over a time period wherein statistically trendsmay be established.

Example 16 Pain Management in Conjunction with Visualization of theIndividual's Own Organs

In another embodiment of the present invention, the individual isenabled to view his/her own organ[s] rather than a standardized organ ofan unknown person or a graphical model of the organ. As an example, theindividual who has undergone a thallium contrast magnetic resonanceimage study of the heart may capture the images of his/her heart inaction at a selected time when such a study was undertaken, save saidgraphics/video images in a secure database such as on a central server,an escrow server or even a mobile device. Upon experiencing heart painshe/she is enabled to select the image from within the mobile devicestorage/database or down load it from a server, manipulate it, annotatethe video/graphics image with notes to indicate pain location and otherfactors, thus creating a living visual personal health record that is ofsignificant value in personal health management. The selectedinformation is enabled for collaboratively being viewed by theindividual and the health professional such that in the event the painis life threatening, a selected dose of the drug that is pertinent tosuch treatment is administered by the individual himself or by thehealth professional in conjunction with a wearable drug delivery systemsuch as the intelligent skin patch system 420 or 440 ensuring that thedrug is delivered for certain selected conditions through the skin andfor other selected conditions through the catheter. By extension, othertypes of intelligent measurement, monitoring and drug delivery systemsmay be used for treatment of the medical condition independently or inconjunction with standardized or personal visual images of the relevantorgan. The present invention takes away the exclusivity of personalhealth records such as X ray, MRI images for health care professional'suse only and makes them readily available by wired or wirelesscommunication means to the individual for active personal healthmanagement including using said images, uraphics, data, video and otherinformation for pain management and other personal health careapplications via a mobile device such as a cellular telephone, PDA, laptop computer, a stationary device, an intelligent appliances andservers.

Referring now to FIG. 5, a personal health management record for anindividual is shown containing information related to the date and timeat which various measurements, monitoring and other activities takeplace or are intended to take place. As one example the healthmanagement record may be organized in one or more formats whereas atabular format is shown for illustrative purposes. Such a table maycontain the measured values of the blood glucose BG level of anindividual at one or more points in time including a control value or anormal value. The table may also shown the food ingestion activity suchas the type, quantity, location and other information related to thefood ingested by the individual including alcohol, tobacco and othersubstances. The location may be at home or at a restaurant including afast food restaurant. In addition, the table may contain informationrelated to the types of medications, the dosage/quantity and the timesat which said medications are ingested. Further, the table mayadditionally contain physical/mental activity information such as thetype, duration and other information such the calories expended. Theinformation such as the personal health symptoms, duration and type maybe included in the table. The times and dosages of the insulin infusedby various methods is also recorded. The general and specific actionstaken by the individual acting by him/her self or in conjunction with anintelligent appliance, a mobile device, a stationary device, a serverand a health professional may also be recorded. The information also maycontain individual identification, health care provider information,insurance information, RF ID information, mobile device information,emergency contact information and all other information that is relevantand useful. The tabular format is for illustrative purposes but theintention is that the information may be recorded in one or moredatabases organized in one or more formats including look up tables foreasy reference. The information is intended to be maintained locallywithin the local processor/storage and or within another intelligentappliance, mobile device, stationary device and one or more servers foruse singly or in combination by wired or wireless communication.

The foregoing descriptions of specific embodiments of the presentinvention have been presented for purposes of illustration anddescription. They are not intended to be exhaustive or to limit theinvention to the precise forms disclosed, and it should be understoodthat many modifications and variations are possible in light of theabove teaching. The embodiments were chosen and described in order tobest explain the principles of the invention and its practicalapplication, to thereby enable others skilled in the art to best utilizethe invention and various embodiments with various modifications as aresuited to the particular use contemplated. It is intended that the scopeof the invention be defined by the Claims appended hereto and theirequivalents.

What is claimed is:
 1. A method comprising: receiving a specimen from abody of a user via a port of a device; analyzing the specimen andgenerating processed information via a processor wherein the analyzingincludes correlating parameters of the specimen with one or more ofbiological parameters and health information of the body; automaticallydetermining a location of the device; making an information inquiry toan information server via the processor, the information server havingthe health information of the body which includes gastronomicinformation which is displayed to the user via the device; identifyingthe user via biometric authentication information related to the userwhich is maintained at least by each of the device, a central server,and an escrow server such that specified authentication information ofthe user is separated from other authentication information of the usersuch that authentication of the user is layered to provide a secureauthentication system; controlling a delivery system of the device viathe processor to administer at least one composition for use in treatingthe body, wherein the composition is administered under control of theprocessed information; and storing in a memory on the device or in amemory on a server the composition delivery administration.
 2. Themethod of claim 1, wherein the administering includes one or more ofautomatically administering and administering under manual control ofthe user.
 3. The method of claim 1, wherein the processed informationincludes a plurality of dosages corresponding to the parameters of thespecimen, wherein the composition is administered under at least one ofthe plurality of dosages.
 4. The method of claim 1, comprisinggenerating control signals one or more of automatically and in responseto an input from the user, wherein the control signals are configured tocontrol one or more of devices coupled to the body, devices implanted inthe body, devices coupled to the processor and the administering.
 5. Themethod of claim 4, wherein the processed information includesinformation of the at least one composition, wherein the information ofthe at least one composition includes one or more of compositionidentification information, an amount released, and a time of release.6. The method of claim 4, comprising a reservoir coupled to theprocessor, wherein the reservoir is configured to contain at least onecomposition for use in treating the body.
 7. The method of claim 1,wherein the composition is administered as one or more of a liquid, anatomized liquid, and a vapor.
 8. The method of claim 1, whereinreceiving the specimen includes one or more of receiving a substratethat includes the specimen and automatically taking the specimen fromthe body.
 9. The method of claim 1, wherein the specimen comprises asubstrate that includes a blood sample, wherein the processedinformation includes one or more of an insulin level and a glucose levelof the blood sample.
 10. The method of claim 1, comprising one or moreof transmitting and receiving one or more of the processed information,the biological parameters, and the health information.
 11. The method ofclaim 1, wherein the analyzing includes distributed analyzing among thedevice or at least one remote device.
 12. The method of claim 1,comprising displaying one or more of a raw version and a processedversion of one or more of the biological parameters, the processedinformation, and the health information.
 13. The method of claim 1,comprising receiving biometric identification information of the user,the biometric identification information including one or more of voicesignals, photographic data, handwriting data, finger print data, andretinal data.
 14. The method of claim 1, comprising communicating with aplurality of health management devices, wherein the biologicalparameters acquired by the health management devices are received by thedevice.
 15. The method of claim 14, comprising controlling the healthmanagement devices.
 16. The method of claim 1, comprising receivingcontrol data from a remote device, wherein the control data controls oneor more of the analyzing and the administering.
 17. The method of claim1, comprising receiving identification information of the user from aremote device.
 18. The method of claim 17, comprising one or more ofreceiving from and transmitting to the identification device one or moreof the health information and the biological parameters.
 19. The methodof claim 1, comprising authenticating one or more of the device and theuser.
 20. The method of claim 1, comprising communicating alertinformation in response to the processed information, wherein the alertinformation includes one or more of a message, a visual alert, anaudible alert, and a vibratory alert communicated to the user, whereinthe alert information includes one or more of voice data, text, graphicsdata, multimedia information, and an electronic signal transmitted to aremote device located one or more of on the body, in a home, in anoffice, and at a medical treatment facility.
 21. The method of claim 1,wherein the biological parameters include one or more of current andhistorical biological information of the user comprising one or more ofweight, height, age, body mass index, medical analyses results, bodyfluid analyses, blood analyses results, electrical activity of the body,heart activity, heart rate, and blood pressure.
 22. The method of claim1, wherein the health information includes one or more of current andhistorical health information of the user, wherein the healthinformation includes one or more of dietary data, types of foodconsumed, amounts of food consumed, medications consumed, times of foodconsumption, physical activity, exercise regimen, work schedule,activity schedule, and sleep schedule.
 23. The method of claim 1,wherein the analysis includes correlating one or more of parameters ofthe specimen, the health information, and the biological parameters withcategorical data of the user, wherein the categorical data includes oneor more of data of an age category of the user, data of a body type ofthe user, and parametric data of the user.
 24. The method of claim 1,comprising outputting one or more of results of the analysis, thebiological parameters, and the health information, wherein results ofthe analysis comprise suggestions regarding one or more of dietary data,types of food to be consumed, amounts of food to be consumed,medications to be consumed, times food is to be consumed, physicalactivity, exercise regimen, activity schedule, sleep schedule, andchanges to the health information to improve health of the user.
 25. Themethod of claim 1, comprising converting one or more of data of thespecimen, the biological parameters, and the health information from afirst form to a second form.
 26. The method of claim 1, comprisingcorrelating one or more of the biological parameters, the healthinformation, the processed information, and the administering of the atleast one composition to the body with the information of the locationto one or more of adjust administration of the composition to the bodyand recommend actions for controlling health of the body, wherein therecommended actions include one or more of actions of food ingestion,medication ingestion, and physical activity.
 27. The method of claim 1,wherein the processed information includes one or more administrationparameters of the administered composition, the administrationparameters including composition, quantity, volume, pressure, rate,flow, temperature, and duration of administration.
 28. The method ofclaim 1, wherein the device is a mobile device.
 29. The method of claim28, wherein the mobile device is a cellular telephone.
 30. Anon-transitory computer readable medium including executableinstructions which when executed in a processing system provide drugdelivery by: receiving a specimen form a body of a user via a port of adevice; analyzing the specimen and generating processed information,wherein the analyzing includes correlating parameters of the specimenwith one or more of the biological parameters and health information ofthe body automatically determining a location of the device; making aninformation inquiry to an information server via the processor, theinformation server having the health information of the body whichincludes gastronomic information which is displayed to the user via thedevice; identifying the user via biometric authentication informationrelated to the user which is maintained at least by each of the device,a central server, and an escrow server such that specifiedauthentication information of the user is separated from otherauthentication information of the user such that authentication of theuser is layered to provide a secure authentication system; controlling adelivery system of the device to administer at least one composition foruse in treating the body, wherein the composition is administered undercontrol of the processed information; and storing in a memory on thedevice or in a memory on a server the composition deliveryadministration.